More relaxed diabetes control targets may still reduce the risk of dementia in older people

Publicly released:
Australia; International; VIC

Australian and international researchers have worked out the type 2 diabetes control targets that help reduce the risk of dementia in older people. Previous studies have suggested that overly strict control of type 2 diabetes in older people can actually increase the risk of harm, including death, and this new study confirms that this control can be more relaxed and still have benefits for reducing the risk of dementia. The study found that for people aged 50 years or older with type 2 diabetes, those whose levels of glycemic control were mostly 9% or greater had the greatest risk of dementia. Current Australian guidelines recommend a general target of at least 7.0% for most patients with diabetes, although they do note that targets need to be individualised to a greater or lesser degree.

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Research JAMA, Web page Please link to the article in online versions of your report (the URL will go live after the embargo ends).
Journal/
conference:
JAMA Neurology
Research:Paper
Organisation/s: Monash University
Funder: This study was funded by grants R01AG067199 from the NIA (Dr Gilsanz); R01-AG063391: Optimizing Medical Decision Making for Older Patients with Type 2 Diabetes from the NIA (Dr Karter); and P30 DK092924 from the NIDDK (Dr Karter).
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