Moderna vaccine generates higher antibody levels than Pfizer COVID-19 vaccine

Publicly released:
International

This study of healthcare workers in Belgium has found that antibody levels are higher after vaccination with the Moderna COVID-19 vaccine than with the Pfizer vaccine. The study included people who had previously tested positive for COVID-19 along with those who had not been infected and found higher antibody levels in both groups. The authors say the higher mRNA content in the Moderna vaccine and the longer interval between doses (4 weeks vs 3 weeks for Pfizer) might explain this difference. Whether this difference translates to a difference in the duration of protection, the protection against variants of concern, and the risk of transmission needs further investigation, the authors say.

Media release

From: JAMA

JAMA

Comparison of SARS-CoV-2 Antibody Response Following Vaccination With BNT162b2 and mRNA-1273

This study compares the immune responses to the Pfizer-BioNTech and Moderna COVID-19 vaccines in health care workers in Belgium.

Attachments

Note: Not all attachments are visible to the general public. Research URLs will go live after the embargo ends.

Research JAMA, Web page Please link to the article in online versions of your report
Journal/
conference:
JAMA
Research:Paper
Organisation/s: Ziekenhuis Oost-Limburg, Belgium
Funder: Roche Diagnostics International Ltd provided test reagents and Interreg Euregio Meuse-Rhine provided financial support (grant EMR-187 CODAP).
Media Contact/s
Contact details are only visible to registered journalists.