Ivermectin fails to stop COVID-19 becoming severe

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Bundesministerium für Finanzen, CC BY 2.0 <https://creativecommons.org/licenses/by/2.0>, via Wikimedia Commons
Bundesministerium für Finanzen, CC BY 2.0 <https://creativecommons.org/licenses/by/2.0>, via Wikimedia Commons

A trial in Malaysia has found that ivermectin fails to stop severe disease developing when it is given to high risk people with mild to moderate COVID-19. Ivermectin is a controversial anti-parasitic drug that has been touted by some as a potential COVID-19 treatment. The authors say the study findings do not support the use of ivermectin for patients with COVID-19.

Media release

From: JAMA

Assessing Efficacy of Ivermectin on Disease Progression in Patients With COVID-19

JAMA Internal Medicine
Original Investigation

Efficacy of Ivermectin Treatment on Disease Progression Among Adults With Mild to Moderate COVID-19 and Comorbidities

What The Study Did: In this open-label randomized clinical trial of high-risk patients with COVID-19 in Malaysia, a 5-day course of oral ivermectin administered during the first week of illness didn’t reduce the risk of developing severe disease compared with standard care alone.

Authors: Steven Chee Loon Lim, M.R.C.P., of  the Raja Permaisuri Bainun Hospital in Perak, Malaysia, is the corresponding author.

(doi:10.1001/jamainternmed.2022.0189)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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JAMA Internal Medicine
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Organisation/s: Raja Permaisuri Bainun Hospital, Malaysia
Funder: Conflict of Interest Disclosures: None reported.
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