If you have an allergic reaction to your first Pfizer dose, should you go back for round 2?

Embargoed until: Publicly released: 2021-07-27 01:00

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CDC

Around four in five people who have a reaction to their first dose of the Pfizer or Moderna vaccine will not react to the second dose, according to a small US study. The researchers followed 159 people who had an allergic reaction to their first mRNA vaccine dose as they went back for their second dose. Thirty-two people, or one in five, had a reaction to their second dose but these were all mild and/or resolved with antihistamines.

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Journal/
conference: JAMA Internal Medicine

Research:Paper

Organisation/s: Vanderbilt University Medical Center, USA

Funder: This work was supported by NIH grant K01 AI125631 (Dr Blumenthal), AHRQ/Patient-Centered Outcomes Research Institute grant 1K12HS026395-01 (Dr Stone), and the Massachusetts General Hospital DOM Transformative Scholar Program (Dr Blumenthal).

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