If mums-to-be are doing it tough, it may affect bub's brain

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Australia; International; VIC
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Aussie and US scientists say babies of mothers who experienced greater socioeconomic disadvantage during pregnancy may have smaller brains than babies of wealthier mothers. The team looked at data from 399 mum-bub pairs from diverse socioeconomic backgrounds, including scans of the babies' brains. They found greater social disadvantage was linked with reductions in the volumes of babies' white matter and gray matter, and a reduction in cortical folding. Although this type of study cannot show that social disadvantage actually caused the changes in brain volume seen, the researchers say the findings suggest the links between poverty and brain development begin in the womb, and early intervention to support bub's brain development should be targetted at struggling families.

Media release

From: JAMA

Prenatal Exposure to Early-Life Adversity, Brain Volumes at Birth

What The Study Did: This study of 280 mother-infant pairs examined whether maternal social disadvantage and psychosocial stress during pregnancy were associated with infant brain volumes at birth.

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Research JAMA, Web page The URL will go live after the embargo ends
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JAMA Network Open
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Organisation/s: Murdoch Children's Research Institute (MCRI), The University of Melbourne, Washington University in St Louis, USA
Funder: This study was funded by grants R01 MH113883, K01 MH122735, and T32 MH100019 from the NIH, the March of Dimes Foundation, grant MI-II-2018-725 from the Children’s Discovery Institute, grant P50 HD103525 from theWashington University Intellectual and Developmental Disability Research Center, and National Alliance for Research on Schizophrenia & Depression Young Investigator Grant 28521 from the Brain and Behavior Research Foundation.
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