How does your allergy history affect your risk of reacting to Pfizer or Moderna vaccines?

Embargoed until: Publicly released: 2021-10-27 02:00

International

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Those with a history of severe allergic reactions, including to vaccines or medications, are more likely to have an allergic reaction to the Pfizer or Moderna COVID-19 vaccines, according to international research. Using vaccination and health data from about 50,000 US health care employees vaccinated in late 2020/early 2021, the researchers say 11.6 per cent of those who had previously reported a severe allergic reaction to a vaccine, medication or allergen had a reaction to at least one of their vaccine doses. 4.7 per cent of those who had no previous allergy history had a reaction. The most common allergic reaction was hives, and most of the allergic reactions to vaccines did not prevent the employees from having their second dose.

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Journal/
conference: JAMA Network Open

Research:Paper

Organisation/s: Brigham and Women’s Hospital, USA

Funder: Dr Li was supported by grant T32AI007306 from the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH). Dr Robinson was supported by the Executive Committee on Research Population Health Sciences Fellowship Award from Massachusetts General Hospital. Dr Blumenthal was supported by grant K01 AI125631 from the NIAID/NIH and by the Massachusetts General Hospital Department of Medicine Transformative Scholar Program.

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