International
People who were taking a GLP-1 RA diabetes/weight loss drug just before or early in their pregnancy are likely to gain more weight during their pregnancy, according to international research. GLP-1 RAs such as Ozempic can't be taken during pregnancy, but the researchers say few studies have been done into how stopping the drug could impact weight gain as the pregnancy continues. Comparing 1344 pregnancies unexposed to a GLP-1 RA with 448 where the mother had ordered the drug between 3 years pre- and 90 days post-conception, the researchers say the women who had taken the drug gained 3.3 kilograms more on average, and had a 65% chance of gaining more than the recommended amount of weight compared to 49% for unexposed pregnancies. They say previous GLP-1 RA use was also linked to a higher risk of preterm delivery, gestational diabetes and blood pressure disorders.
From:
About The Study: In a cohort composed primarily of women with obesity, glucagon-like peptide-1 receptor agonist (GLP-1RA) use with subsequent pre-pregnancy or early pregnancy discontinuation was associated with more gestational weight gain and a higher risk of preterm delivery, gestational diabetes, and hypertensive disorders of pregnancy.
Note: Not all attachments are visible to the general public. Research URLs will go live after the embargo ends.
Sign In
