How diet in older age can influence the risk of dementia

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Photo by jeff ahmadi on Unsplash
Photo by jeff ahmadi on Unsplash

Eating a healthier diet in your older years can reduce the risk of developing dementia, in some cases even for those who are at a higher risk, according to international research. The team followed a cohort of 1865 Swedish over-60s for an average of 8.4 years, looking at how well they adhered to three healthy dietary patterns: a Mediterranean diet, the Alternative Healthy Eating Index - which prioritises fruit, veg, legumes and nuts -, and the reverse Empirical Dietary Inflammatory Index - which focuses on the anti-inflammatory quality of the overall diet. By the end of the study, 240 participants developed dementia. The researchers say a higher-quality diet overall was linked to a lower risk of dementia and a later time for dementia to start. Looking specifically at participants who showed signs in their brain of an increased risk of Alzheimer's, the researchers say greater adherence to the anti-inflammatory diet was still linked to a lower risk of dementia and a later onset of the condition.

News release

From: JAMA

Diet and Dementia Risk in Individuals With Prevalent Neuropathology

About The Study: This cohort study of older adults found that adherence to a dietary pattern with lower inflammatory potential was associated with lower dementia risk among individuals with Alzheimer disease pathology and broader neurobiological risk. These findings reinforce the importance of targeted dietary dementia prevention strategies not only for the general population but also for individuals already at elevated risk.

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conference:
JAMA Network Open
Research:Paper
Organisation/s: Karolinska Institutet, Sweden, University of Ljubljana, Slovenia
Funder: Data collection for the SNAC-K was supported by grant 2021-00178 from the Swedish Research Council, the Swedish Ministry of Health and Social Affairs, and the participating county councils and municipalities; Stiftelsen Dementia (Ms Mrhar); grants 2024:0011 and 2025:0013 from the Foundation for Geriatric Diseases at Karolinska Institutet, 2024:0017 from the Karolinska Institutet Research Foundation, 2024: 0005 from the David and Astrid Hagelén Foundation, and STY-2024/0005 from the Swedish Research Council for Health,Working Life andWelfare (Dr Carballo-Casla); Demensfonden (Dr Triolo); Margaretha af Ugglas’ Foundation (Prof Winblad); and grant 2021-03324 from the Swedish Research Council, the Karolinska Institutet Strategic Research Area in Epidemiology and Biostatistics in 2021 and 2023, and the Karolinska Institutet Strategic Research Area in Neuroscience in 2025 (Dr Vetrano). Dr Fratiglioni was supported by the Swedish Research Council.
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