Do the benefits of a higher protein intake outweigh the risks in those with chronic kidney disease?

Embargoed until: Publicly released: 2024-08-08 01:00

International

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A higher protein intake is associated with a lower risk of death among older people with chronic kidney disease, even though it is associated with faster disease progression, according to international research. Previous research shows eating less protein may slow kidney decline, however eating more protein is associated with various health benefits in older people. The researchers used data from three cohorts of people aged 60+ to compare the associations between protein intake and premature death between people with and without chronic kidney disease. They say among the participants with kidney disease, higher total, animal and plant protein intake was associated with a lower risk of death, however, this association was stronger among people without kidney disease. The researchers say this shows the benefits of protein may outweigh the risks for people with chronic kidney disease because of its other health benefits.

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Journal/
conference: JAMA Network Open

Research:Paper

Organisation/s: Karolinska Institutet and Stockholm University, Sweden

Funder: The current analysis of the Study on Cardiovascular Health, Nutrition and Frailty in Older Adults in Spain (Seniors-ENRICA) acohorts was supported by the Institute of Health Carlos III, the Secretary of Research, Development, and Innovation, and Fondo de Investigaciones Sanitarias grant 22/1111 from the European Regional Development Fund/European Social Fund; grant PLEC2022-009352 from the Ministry of Science, Innovation, and Universities and the European Union “Next Generation EU/PRTR”; and grants PMPTA22/00107 and MPTA23/ 00012 from the Institute of Health Carlos III, CDTI, and the European Union “Next Generation EU/PRTR”. Data collection for the Swedish National study on Aging and Care in Kungsholmen (SNAC-K) was supported by grant 2021-00178 from the Swedish Research Council (ongoing and current), the Swedish Ministry of Health and Social Affairs, and the participating County Councils and Municipalities. Dr Carballo-Casla received funding for project number 2023-02068 from the Foundation for Geriatric Diseases at Karolinska Institutet. Dr Beridze received funding from the Sigurd & Elsa Goljes Memorial Foundation. Dr Vetrano received funding from the Swedish Research Council. Dr Calderón-Larrañaga received funding for project 2021-06398 from the Swedish Research Council, project 2021-00256 from the Swedish Research Council for Health,Working Life, andWelfare, and an SFOepi consolidator bridging grant from Karolinska Institutet.

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