Antidepressants based on your genetics may be more effective than non-drug depression treatments

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US researchers say people who are treated for depression with medication chosen for them based on their genetics might see more benefits in the long term than those on non-drug-based standard care. The researchers tested 1,460 people's genetics, 603 of whom were deemed suitable for medication based on their genes, while 354 recieved standard non-drug-based depression treatment. The team says that while there was no difference in depressive symptoms between the two groups at a three month check-up, they found that after six months the group on genetics-based antidepressants were more likely to be in remission than the standard treatment group.

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Research JAMA, Web page The URL will go live after the embargo ends
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JAMA Network Open
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Organisation/s: Nemours Children’s Health,USA, Vanderbilt University Medical Centre, USA
Funder: This study was supported by the NIH under award numbers U01HG007269, U01HG010232, U01HG010248, U01HG010231, U01HG010245, and U01HG010225 (Dr Liu) and by the NIH IGNITE Network Genome Medicine Knowledge Base.
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