A nerve protecting drug combination could improve stroke outcomes

Publicly released:
Australia; International; NSW
Image by Raman Oza from Pixabay
Image by Raman Oza from Pixabay

A fast-acting drug combination that works to protect the cells in the brain, could help improve patients' symptoms after a stroke, according to a study from China. The study found that the combination of edaravone and dexborneol, which together have antioxidant and anti-inflammatory activity, could significantly improve stroke outcomes compared to placebo. The drugs can be placed under the tongue, which makes them useful even in patients who are unconscious, disabled, or unable to swallow. An accompanying editorial by Australian experts says the findings are a 'remarkable result' but also highlights potential conflicts of interest among the authors.

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Research JAMA, Web page
Editorial / Opinion JAMA, Web page
Journal/
conference:
JAMA Neurology
Research:Paper
Organisation/s: George Institute for Global Health, Peking University Third Hospital, Simcere Pharmaceutical Group Limited China,
Funder: This trial was sponsored and funded by grant SIM1911 from Simcere Pharmaceutical and grant 2022YFA1303000 from National Key R&D Program of China
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