Plasma from recovered COVID patients works better if it has more antibodies

Embargoed until: Publicly released:
Peer-reviewed: This work was reviewed and scrutinised by relevant independent experts.

Observational study: A study in which the subject is observed to see if there is a relationship between two or more things (eg: the consumption of diet drinks and obesity). Observational studies cannot prove that one thing causes another, only that they are linked.

People: This is a study based on research using people.

COVID patients who receive blood plasma with higher SARS-CoV-2 antibody levels had a lower risk of death than those who received plasma with lower antibody levels, according to US research. This sort of treatment, known as convalescent plasma, has been widely used to treat COVID-19, and it involved using blood plasma from recovered COVID-19 patients to treat current patients, in the hope that the plasma contains potentially therapeutic antibodies that can be passed on the patient.

Journal/conference: New England Journal of Medicine

Link to research (DOI): 10.1056/NEJMoa2031893

Organisation/s: Mayo Clinic, USA

Funder: Funded by the Department of Health and Human Services and others; ClinicalTrials.gov number, NCT04338360

Attachments:

  • Massachusetts Medical Society
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