Media ReleaseFrom: Wiley-Blackwell From: British Journal of Clinical Pharmacology
Analysis Examines Safety of Antidepressant Use During Pregnancy
Use of fluoxetine—the most commonly prescribed antidepressant—during pregnancy is linked with a slightly increased risk of malformations in infants, according to a recent analysis of published studies.
In the analysis of 16 studies, infants exposed to fluoxetine during the first trimester had an 18% increased relative risk of major malformations and a 36% increased relative risk of cardiovascular malformations. There were no significant observations of other system-specific malformations in the nervous system, eye, urogenital system, digestive system, respiratory system, or musculoskeletal system.
The findings are published in the British Journal of Clinical Pharmacology.