COVID-19 risks higher for those with Down Syndrome

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Observational study: A study in which the subject is observed to see if there is a relationship between two or more things (eg: the consumption of diet drinks and obesity). Observational studies cannot prove that one thing causes another, only that they are linked.

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Those with Down syndrome could be 10 times more likely to die from COVID-19, and four times more likely to be hospitalised by it, according to international researchers, who say this group of people should be strategically protected. The researchers analysed data from a study of 8.26 million adults in the UK and say heart issues and care home living among those with Down Syndrome contributes some, but not all of the risk, and further researcher must be taken to understand their elevated health risks.

Journal/conference: Annals of Internal Medicine

Link to research (DOI): 10.7326/M20-4986

Organisation/s: Nuffield Department of Primary Care Health Sciences, UK

Funder: By the NIHR (United Kingdom). Dr. Hemingway is an NIHR Senior Investigator and is funded by grant LOND1 from the NIHR University College London Hospitals Biomedical Research Centre and Health Data Research UK. Dr. Keogh is supported by a UKRI Future Leaders Fellowship (MR/S017968/1).

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  • American College of Physicians
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